San Francisco 49ers at Los Angeles Rams — Week 1 Odds, Injuries & Prediction

San Francisco 49ers @ Los Angeles Rams: live odds, injury report, team rankings comparison, and win probability for this matchup.

Thu, Sep 10 · 8:35 PM ET · Netflix

Odds (DraftKings): LAR -3.5 · ML SF +164 / LAR -198 · O/U 48.5

Model prediction

Predicted winner: Los Angeles Rams - SF 9% / LAR 91%

Team stats comparison (rank out of 32)

	SF offense	LAR offense	Edge
Total yards	#7	#1	home edge (6)
Rush yards	#24	#7	home edge (17)
Pass yards	#5	#1	home edge (4)

	SF defense	LAR defense	Edge
Total yards allowed	#20	#17	home edge (3)
Rush yards allowed	#11	#12	away edge (1)
Pass yards allowed	#25	#19	home edge (6)

Injury report

• Christian McCaffrey (SF · RB) - questionable - Calf/leg tightness (undisclosed body part)
• Mike Evans (SF · WR) - questionable - Quad strain
• George Kittle (SF · TE) - out - Torn Achilles tendon
• Ricky Pearsall (SF · WR) - out - PCL knee surgery - season-ending
• Nick Bosa (SF · Edge) - out - Knee tendinitis (surgically repaired right knee)

San Francisco 49ers full schedule · Los Angeles Rams full schedule · See this week's full NFL odds and predictions on Blitz Odds