Seattle Seahawks at San Francisco 49ers — Week 12 Odds, Injuries & Prediction

Seattle Seahawks @ San Francisco 49ers: live odds, injury report, team rankings comparison, and win probability for this matchup.

Sun, Nov 29 · 4:25 PM ET · FOX

Odds (DraftKings): SF -1.5 · ML SEA -110 / SF -121 · O/U 47.5

Model prediction

Predicted winner: Seattle Seahawks - SEA 92% / SF 8%

Team stats comparison (rank out of 32)

	SEA offense	SF offense	Edge
Total yards	#8	#7	home edge (1)
Rush yards	#10	#24	away edge (14)
Pass yards	#8	#5	home edge (3)

	SEA defense	SF defense	Edge
Total yards allowed	#6	#20	away edge (14)
Rush yards allowed	#3	#11	away edge (8)
Pass yards allowed	#10	#25	away edge (15)

Injury report

• Christian McCaffrey (SF · RB) - questionable - Calf/leg tightness (undisclosed body part)
• Mike Evans (SF · WR) - questionable - Quad strain
• George Kittle (SF · TE) - out - Torn Achilles tendon
• Ricky Pearsall (SF · WR) - out - PCL knee surgery - season-ending
• Nick Bosa (SF · Edge) - out - Knee tendinitis (surgically repaired right knee)

Seattle Seahawks full schedule · San Francisco 49ers full schedule · See this week's full NFL odds and predictions on Blitz Odds