San Francisco 49ers at Los Angeles Chargers — Week 15 Odds, Injuries & Prediction
San Francisco 49ers @ Los Angeles Chargers: live odds, injury report, team rankings comparison, and win probability for this matchup.
Thu, Dec 17 · 8:15 PM ET · Prime Video
Odds (DraftKings): LAC -2.5 · ML SF +120 / LAC -142 · O/U 47.5
Model prediction
Predicted winner: San Francisco 49ers - SF 63% / LAC 37%
Blitz Edge: why the model likes San Francisco 49ers
The model gives San Francisco 49ers a 63% chance to win this one. The biggest factors: SF's rush offense (#6) has a 16-spot edge over LAC's rush defense (#22), and SF's total defense (#7) has a 14-spot edge over LAC's total offense (#21).
LAC is also dealing with Rashawn Slater (LT) listed as out, which tips things further SF's way. Note: the sportsbook favorite (LAC) disagrees with this pick.
Team stats comparison (rank out of 32)
| SF offense | LAC offense | Edge |
|---|
| Total yards | #7 | #21 | away edge (14) |
| Rush yards | #6 | #9 | away edge (3) |
| Pass yards | #8 | #24 | away edge (16) |
| SF defense | LAC defense | Edge |
|---|
| Total yards allowed | #7 | #16 | away edge (9) |
| Rush yards allowed | #9 | #22 | away edge (13) |
| Pass yards allowed | #11 | #14 | away edge (3) |
Injury report
- Ladd McConkey (LAC · WR) - questionable - Foot
- Ricky Pearsall (SF · WR) - out - PCL knee surgery - season-ending
- Nick Bosa (SF · Edge) - out - Calf
- Christian Kirk (SF · WR) - out - Calf
- Sam Okuayinonu (SF · DE) - out - Foot injury - on injured reserve
- Alfred Collins (SF · DT) - out - Torn patellar tendon (knee) - season-ending
- De'Zhaun Stribling (SF · WR) - out - Ankle - deltoid sprain, surgically repaired - on injured reserve
- Jake Tonges (SF · TE) - out - MCL knee injury - on injured reserve, season-ending
- Demarcus Robinson (SF · WR) - out - High ankle sprain
- Brandon Aiyuk (SF · WR) - out - Personal
- Rashawn Slater (LAC · LT) - out - Ankle
- Tyler Biadasz (LAC · C) - out - Torn ACL - season-ending
- Dalevon Campbell (LAC · WR) - out - Leg
- KeAndre Lambert-Smith (LAC · WR) - out - Hamstring
- David Njoku (LAC · TE) - out - Fibula (lower leg) - on injured reserve
- Charlie Kolar (LAC · TE) - out - Broken forearm - surgery, on injured reserve
- Brenen Thompson (LAC · WR) - out - Quadriceps
San Francisco 49ers full schedule ·
Los Angeles Chargers full schedule ·
See this week's full NFL odds and predictions on Blitz Odds