Detroit Lions at Arizona Cardinals — Week 5 Odds, Injuries & Prediction
Detroit Lions @ Arizona Cardinals: live odds, injury report, team rankings comparison, and win probability for this matchup.
Sun, Oct 11 · 4:25 PM ET · FOX
Odds (DraftKings): DET -8.5 · ML DET -395 / ARI +310 · O/U 48.5
Model prediction
Predicted winner: Arizona Cardinals - DET 36% / ARI 64%
Team stats comparison (rank out of 32)
| DET offense | ARI offense | Edge |
|---|
| Total yards | #10 | #26 | away edge (16) |
| Rush yards | #11 | #24 | away edge (13) |
| Pass yards | #7 | #28 | away edge (21) |
| DET defense | ARI defense | Edge |
|---|
| Total yards allowed | #31 | #14 | home edge (17) |
| Rush yards allowed | #28 | #22 | home edge (6) |
| Pass yards allowed | #31 | #14 | home edge (17) |
Injury report
- D.J. Reed (DET · CB) - active - Foot
- Jeremiyah Love (ARI · RB) - active - High ankle sprain
- Xavier Weaver (ARI · WR) - active - Hamstring
- Ihmir Smith-Marsette (ARI · WR) - active - Ankle
- Christian Mahogany (DET · G) - questionable - Hip (knee injury that migrated to the hip)
- Blake Miller (DET · RT) - questionable - Knee
- Max Melton (ARI · CB) - questionable - Toe
- Brian Branch (DET · S) - out - Torn Achilles - on reserve/PUP
- Kerby Joseph (DET · S) - out - Knee injury (lingering from 2025) - on reserve/PUP
- Payton Turner (DET · DE) - out - Back
- Isiah Pacheco (DET · RB) - out - Back - surgery (loose body pressing on a nerve), on injured reserve
- Cade Mays (DET · C) - out - Fractured wrist - on injured reserve, designated to return
- Avonte Maddox (DET · CB) - out - Foot - season-ending surgery
- James Conner (ARI · RB) - out - Ankle - on injured reserve (designated to return)
- Reggie Virgil (ARI · WR) - out - Coach's Decision
- Garrett Williams (ARI · CB) - out - Torn Achilles - recovering
- Will Johnson (ARI · CB) - out - Neck
Detroit Lions full schedule ·
Arizona Cardinals full schedule ·
See this week's full NFL odds and predictions on Blitz Odds