San Francisco 49ers at Seattle Seahawks — Week 5 Odds, Injuries & Prediction

San Francisco 49ers @ Seattle Seahawks: live odds, injury report, team rankings comparison, and win probability for this matchup.

Sun, Oct 11 · 4:25 PM ET · FOX

Odds (DraftKings): SEA -3.5 · ML SF +170 / SEA -205 · O/U 48.5

Model prediction

Predicted winner: Seattle Seahawks - SF 7% / SEA 93%

Team stats comparison (rank out of 32)

	SF offense	SEA offense	Edge
Total yards	#7	#8	away edge (1)
Rush yards	#24	#10	home edge (14)
Pass yards	#5	#8	away edge (3)

	SF defense	SEA defense	Edge
Total yards allowed	#20	#6	home edge (14)
Rush yards allowed	#11	#3	home edge (8)
Pass yards allowed	#25	#10	home edge (15)

Injury report

• Christian McCaffrey (SF · RB) - questionable - Calf/leg tightness (undisclosed body part)
• Mike Evans (SF · WR) - questionable - Quad strain
• George Kittle (SF · TE) - out - Torn Achilles tendon
• Ricky Pearsall (SF · WR) - out - PCL knee surgery - season-ending
• Nick Bosa (SF · Edge) - out - Knee tendinitis (surgically repaired right knee)

San Francisco 49ers full schedule · Seattle Seahawks full schedule · See this week's full NFL odds and predictions on Blitz Odds